Table 2. Effect of 2155-14, 2155-18, and vemurafenib on viability of human melanoma cells and melanocytes and murine melanoma cells and fibroblasts. All results are IC₅₀, µM (n=3). NT - not tested, M - male, F - female. M14 - ^G12CNRAS metastatic, WM266-4 - ^V600DBRAF/-/-PTEN metastatic, SKMEL28 - ^V600EBRAF/^R24CCDK4 primary, WM115 - ^V600DBRAF/-/-PTEN primary. Values reported previously elsewhere are indicated by citation numbers